CBMN - Conference du Dr Pierre-Damien Denechaud (I2MC, Toulouse)

Le 21 mai prochain, le Dr Pierre-Damien Denechaud (I2MC, Toulouse) est l'invité du Pr Matthieu Raoux et du CBMN.

Il présentera sa conférence "Adipose lipid and lipolysis, more than storage: intracellular and inter-organ playersAdvancing structural cell biology with expansion microscopy".

Introduction and abstract

I obtained my PhD from the University of Paris 7 in 2009. I did my thesis on the hepatic glucose
sensor ‘ChREBP’ under the supervision of Dr Catherine Postic at the Institut Cochin. I then joined the
laboratory of Prof. Reuben Shaw at the Salk Institute (CA, USA) and then that of Prof. Lluis Fajas at
the Institute of Molecular Genetics in Montpellier (France) and then at the Department of Physiology
at the University of Lausanne (Switzerland). These 2 laboratories are internationally recognised for
their work and expertise in metabolism and cancer. In 2018, I joined Prof. Dominique Langin's
laboratory at the I2MC in Toulouse, where I am developing my research. I am interested in inter-
organ dialogue in the context of type 2 diabetes and obesity, and in particular the role and
importance of adipocyte lipolysis in this metabolic coordination. We have demonstrated the
importance of lipolysis in controlling thermogenesis in brown adipose tissue, and are developing
projects showing the crucial role of adipose tissue-liver and adipose tissue-pancreas dialogue via
adipocyte lipolysis

Contact

• Matthieu Raoux